IJOTM 2008-6490 7 3 2016 07 1 Human Split-Thickness Skin Allograft from Brain-Dead Donors 188 191 EN A Khodadadi O Olang A Makhlough B Nozary Heshmati F Azmoudeh Ardalan SA Tavakoli Iranian Tissue Bank Research Center, Tehran University of Medical Sciences, Tehran, Iran. amirtavakoli1@yahoo.com 2014 11 01 Background: Looking for an appropriate skin substitute for temporary and permanent coverage of wounds remains one of the main obstacles of medical researchers.Objective: To investigate the rate of inflammation, symbiosis, and survival of grafted allograft skin from brain-dead donors (BDDs) in rabbits.Methods: After receiving negative serologic tests of BDDs, we prepared partial thickness skin grafts. They were then used in treating wounds of 5 rabbits in comparison with split-thickness skins taken from cardiac dead donors.Results: On histopathological examinations, we found no difference between the skins. All samples were separated from the baseline in 15–20 days.Conclusion: Gamma-irradiated freeze-dried human split-thickness skin taken from BDDs is safe and can be used for the treatment of deep skin burns.